Seizure likelihood varies with day-to-day variations in sleep duration in patients with refractory focal epilepsy


The results from this paper suggest that day-to-day deviations from regular sleep duration correlates with changes in seizure probability. Sleeping longer, by 1·66 ± 0·52 h, may offer protective effects for patients with refractory focal epilepsy, reducing seizure risk. Furthermore, the occurrence of a seizure may disrupt sleep patterns by elongating sleep and, if the seizure occurs during sleep, reducing its quality.


Katrina L. Dell, Daniel E. Payne, Vaclav Kremen, Matias I. Maturana, Vaclav Gerla, Petr Nejedly, Gregory A. Worrell, Lhotska Lenka, Filip Mivalt, Raymond C. Boston, Benjamin H. Brinkmann, Wendyl D’Souza, Anthony N. Burkitt, David B. Grayden, Levin Kuhlmann, Dean R. Freestone, and Mark J. Cook.

Published on 4 June 2021


Access: Open

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